Cargando…
Colorectal cancer treatment in octogenarians: elective or emergency surgery?
BACKGROUND: The purpose of this research was to assess the characteristics of octogenarian patients with colorectal cancer and compare specific outcomes due to different types of surgical procedures used to treat the disease. METHODS: A total of 346 octogenarian patients undergoing surgery for color...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302045/ https://www.ncbi.nlm.nih.gov/pubmed/25519055 http://dx.doi.org/10.1186/1477-7819-12-386 |
_version_ | 1782353728178749440 |
---|---|
author | Ming-gao, Guo Jian-zhong, Di Yu, Wang You-ben, Fan Xin-Yu, Huang |
author_facet | Ming-gao, Guo Jian-zhong, Di Yu, Wang You-ben, Fan Xin-Yu, Huang |
author_sort | Ming-gao, Guo |
collection | PubMed |
description | BACKGROUND: The purpose of this research was to assess the characteristics of octogenarian patients with colorectal cancer and compare specific outcomes due to different types of surgical procedures used to treat the disease. METHODS: A total of 346 octogenarian patients undergoing surgery for colorectal cancer between April 2000 and April 2010 were retrospectively assessed according to elective (n = 261) or emergent (n = 85) admission group. The two groups were compared for clinical variables, surgical procedures, morbidity and mortality, ICU admission, length of hospital stay and overall survival. RESULTS: The two groups had similar comorbidities. The emergent group had a more advanced Dukes’ stage, higher American Society of Anesthesiologists grading, lower anastomosis rate (40.2 vs 80.1%), higher stoma rate (30.6 vs 9.6%), more complications (71.8 vs 43.3%), nine days longer length of hospital stay and higher (82.4% vs 36.4%) ICU admission rate. Overall mortality was 9.5%, with a higher mortality rate in the emergent group (30.6%) than the elective group (3.1%). CONCLUSIONS: Octogenarians who undergo elective colorectal cancer surgery have better results than those requiring emergent surgery, but both are quite acceptable and we recommend surgical intervention should not be delayed. |
format | Online Article Text |
id | pubmed-4302045 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-43020452015-01-22 Colorectal cancer treatment in octogenarians: elective or emergency surgery? Ming-gao, Guo Jian-zhong, Di Yu, Wang You-ben, Fan Xin-Yu, Huang World J Surg Oncol Research BACKGROUND: The purpose of this research was to assess the characteristics of octogenarian patients with colorectal cancer and compare specific outcomes due to different types of surgical procedures used to treat the disease. METHODS: A total of 346 octogenarian patients undergoing surgery for colorectal cancer between April 2000 and April 2010 were retrospectively assessed according to elective (n = 261) or emergent (n = 85) admission group. The two groups were compared for clinical variables, surgical procedures, morbidity and mortality, ICU admission, length of hospital stay and overall survival. RESULTS: The two groups had similar comorbidities. The emergent group had a more advanced Dukes’ stage, higher American Society of Anesthesiologists grading, lower anastomosis rate (40.2 vs 80.1%), higher stoma rate (30.6 vs 9.6%), more complications (71.8 vs 43.3%), nine days longer length of hospital stay and higher (82.4% vs 36.4%) ICU admission rate. Overall mortality was 9.5%, with a higher mortality rate in the emergent group (30.6%) than the elective group (3.1%). CONCLUSIONS: Octogenarians who undergo elective colorectal cancer surgery have better results than those requiring emergent surgery, but both are quite acceptable and we recommend surgical intervention should not be delayed. BioMed Central 2014-12-17 /pmc/articles/PMC4302045/ /pubmed/25519055 http://dx.doi.org/10.1186/1477-7819-12-386 Text en © Ming-gao et al.; licensee BioMed Central. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Ming-gao, Guo Jian-zhong, Di Yu, Wang You-ben, Fan Xin-Yu, Huang Colorectal cancer treatment in octogenarians: elective or emergency surgery? |
title | Colorectal cancer treatment in octogenarians: elective or emergency surgery? |
title_full | Colorectal cancer treatment in octogenarians: elective or emergency surgery? |
title_fullStr | Colorectal cancer treatment in octogenarians: elective or emergency surgery? |
title_full_unstemmed | Colorectal cancer treatment in octogenarians: elective or emergency surgery? |
title_short | Colorectal cancer treatment in octogenarians: elective or emergency surgery? |
title_sort | colorectal cancer treatment in octogenarians: elective or emergency surgery? |
topic | Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302045/ https://www.ncbi.nlm.nih.gov/pubmed/25519055 http://dx.doi.org/10.1186/1477-7819-12-386 |
work_keys_str_mv | AT minggaoguo colorectalcancertreatmentinoctogenarianselectiveoremergencysurgery AT jianzhongdi colorectalcancertreatmentinoctogenarianselectiveoremergencysurgery AT yuwang colorectalcancertreatmentinoctogenarianselectiveoremergencysurgery AT youbenfan colorectalcancertreatmentinoctogenarianselectiveoremergencysurgery AT xinyuhuang colorectalcancertreatmentinoctogenarianselectiveoremergencysurgery |