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Colorectal cancer treatment in octogenarians: elective or emergency surgery?

BACKGROUND: The purpose of this research was to assess the characteristics of octogenarian patients with colorectal cancer and compare specific outcomes due to different types of surgical procedures used to treat the disease. METHODS: A total of 346 octogenarian patients undergoing surgery for color...

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Autores principales: Ming-gao, Guo, Jian-zhong, Di, Yu, Wang, You-ben, Fan, Xin-Yu, Huang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302045/
https://www.ncbi.nlm.nih.gov/pubmed/25519055
http://dx.doi.org/10.1186/1477-7819-12-386
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author Ming-gao, Guo
Jian-zhong, Di
Yu, Wang
You-ben, Fan
Xin-Yu, Huang
author_facet Ming-gao, Guo
Jian-zhong, Di
Yu, Wang
You-ben, Fan
Xin-Yu, Huang
author_sort Ming-gao, Guo
collection PubMed
description BACKGROUND: The purpose of this research was to assess the characteristics of octogenarian patients with colorectal cancer and compare specific outcomes due to different types of surgical procedures used to treat the disease. METHODS: A total of 346 octogenarian patients undergoing surgery for colorectal cancer between April 2000 and April 2010 were retrospectively assessed according to elective (n = 261) or emergent (n = 85) admission group. The two groups were compared for clinical variables, surgical procedures, morbidity and mortality, ICU admission, length of hospital stay and overall survival. RESULTS: The two groups had similar comorbidities. The emergent group had a more advanced Dukes’ stage, higher American Society of Anesthesiologists grading, lower anastomosis rate (40.2 vs 80.1%), higher stoma rate (30.6 vs 9.6%), more complications (71.8 vs 43.3%), nine days longer length of hospital stay and higher (82.4% vs 36.4%) ICU admission rate. Overall mortality was 9.5%, with a higher mortality rate in the emergent group (30.6%) than the elective group (3.1%). CONCLUSIONS: Octogenarians who undergo elective colorectal cancer surgery have better results than those requiring emergent surgery, but both are quite acceptable and we recommend surgical intervention should not be delayed.
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spelling pubmed-43020452015-01-22 Colorectal cancer treatment in octogenarians: elective or emergency surgery? Ming-gao, Guo Jian-zhong, Di Yu, Wang You-ben, Fan Xin-Yu, Huang World J Surg Oncol Research BACKGROUND: The purpose of this research was to assess the characteristics of octogenarian patients with colorectal cancer and compare specific outcomes due to different types of surgical procedures used to treat the disease. METHODS: A total of 346 octogenarian patients undergoing surgery for colorectal cancer between April 2000 and April 2010 were retrospectively assessed according to elective (n = 261) or emergent (n = 85) admission group. The two groups were compared for clinical variables, surgical procedures, morbidity and mortality, ICU admission, length of hospital stay and overall survival. RESULTS: The two groups had similar comorbidities. The emergent group had a more advanced Dukes’ stage, higher American Society of Anesthesiologists grading, lower anastomosis rate (40.2 vs 80.1%), higher stoma rate (30.6 vs 9.6%), more complications (71.8 vs 43.3%), nine days longer length of hospital stay and higher (82.4% vs 36.4%) ICU admission rate. Overall mortality was 9.5%, with a higher mortality rate in the emergent group (30.6%) than the elective group (3.1%). CONCLUSIONS: Octogenarians who undergo elective colorectal cancer surgery have better results than those requiring emergent surgery, but both are quite acceptable and we recommend surgical intervention should not be delayed. BioMed Central 2014-12-17 /pmc/articles/PMC4302045/ /pubmed/25519055 http://dx.doi.org/10.1186/1477-7819-12-386 Text en © Ming-gao et al.; licensee BioMed Central. 2014 This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Ming-gao, Guo
Jian-zhong, Di
Yu, Wang
You-ben, Fan
Xin-Yu, Huang
Colorectal cancer treatment in octogenarians: elective or emergency surgery?
title Colorectal cancer treatment in octogenarians: elective or emergency surgery?
title_full Colorectal cancer treatment in octogenarians: elective or emergency surgery?
title_fullStr Colorectal cancer treatment in octogenarians: elective or emergency surgery?
title_full_unstemmed Colorectal cancer treatment in octogenarians: elective or emergency surgery?
title_short Colorectal cancer treatment in octogenarians: elective or emergency surgery?
title_sort colorectal cancer treatment in octogenarians: elective or emergency surgery?
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302045/
https://www.ncbi.nlm.nih.gov/pubmed/25519055
http://dx.doi.org/10.1186/1477-7819-12-386
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