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Actin filament-associated protein 1 is required for cSrc activity and secretory activation in the lactating mammary gland

Actin filament-associated protein 1 (AFAP1) is an adaptor protein of cSrc that binds to filamentous actin and regulates the activity of this tyrosine kinase to affect changes to the organization of the actin cytoskeleton. In breast and prostate cancer cells, AFAP1 has been shown to regulate cellular...

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Detalles Bibliográficos
Autores principales:	Cunnick, Jess M, Kim, Stephanie, Hadsell, James, Collins, Stephen, Cerra, Carmine, Reiser, Patti, Flynn, Daniel C, Cho, Youngjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302073/ https://www.ncbi.nlm.nih.gov/pubmed/25043309 http://dx.doi.org/10.1038/onc.2014.205

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