Pathobiology of ovarian carcinomas

Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. We report herein the newly described molecular abnormalities in epithelia...

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Detalles Bibliográficos
Autores principales: Devouassoux-Shisheboran, Mojgan, Genestie, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sun Yat-sen University Cancer Center 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302089/
https://www.ncbi.nlm.nih.gov/pubmed/25556618
http://dx.doi.org/10.5732/cjc.014.10273
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author Devouassoux-Shisheboran, Mojgan
Genestie, Catherine
author_facet Devouassoux-Shisheboran, Mojgan
Genestie, Catherine
author_sort Devouassoux-Shisheboran, Mojgan
collection PubMed
description Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. We report herein the newly described molecular abnormalities in epithelial ovarian cancers (carcinomas). Immunohistochemistry and molecular testing help pathologists to decipher the significant heterogeneity of this disease. Our better understanding of the molecular basis of ovarian carcinomas represents the first step in the development of targeted therapies in the near future.
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spelling pubmed-43020892015-02-06 Pathobiology of ovarian carcinomas Devouassoux-Shisheboran, Mojgan Genestie, Catherine Chin J Cancer Review Ovarian tumors comprise a heterogeneous group of lesions, displaying distinct tumor pathology and oncogenic potentiel. These tumors are subdivided into three main categories: epithelial, germ cell, and sex-cord stromal tumors. We report herein the newly described molecular abnormalities in epithelial ovarian cancers (carcinomas). Immunohistochemistry and molecular testing help pathologists to decipher the significant heterogeneity of this disease. Our better understanding of the molecular basis of ovarian carcinomas represents the first step in the development of targeted therapies in the near future. Sun Yat-sen University Cancer Center 2015-01 /pmc/articles/PMC4302089/ /pubmed/25556618 http://dx.doi.org/10.5732/cjc.014.10273 Text en Chinese Journal of Cancer http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, which allows readers to alter, transform, or build upon the article and then distribute the resulting work under the same or similar license to this one. The work must be attributed back to the original author and commercial use is not permitted without specific permission.
spellingShingle Review
Devouassoux-Shisheboran, Mojgan
Genestie, Catherine
Pathobiology of ovarian carcinomas
title Pathobiology of ovarian carcinomas
title_full Pathobiology of ovarian carcinomas
title_fullStr Pathobiology of ovarian carcinomas
title_full_unstemmed Pathobiology of ovarian carcinomas
title_short Pathobiology of ovarian carcinomas
title_sort pathobiology of ovarian carcinomas
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302089/
https://www.ncbi.nlm.nih.gov/pubmed/25556618
http://dx.doi.org/10.5732/cjc.014.10273
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