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Weekly low-dose methotrexate for reduction of Global Initiative for Asthma Step 5 treatment in severe refractory asthma: study protocol for a randomized controlled trial

BACKGROUND: Patients with chronic severe asthma (CSA) have a crippling disease and current available treatments are not satisfactory. Thus, management of CSA remains a major unmet need. Although the evidence from existing randomized controlled trials fails to support a definite role for immunomodula...

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Detalles Bibliográficos
Autores principales:	Polosa, Riccardo, Bellinvia, Salvatore, Caruso, Massimo, Emma, Rosalia, Alamo, Angela, Kowalski, Marek Leszek, Domingo, Christian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Study Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302097/ https://www.ncbi.nlm.nih.gov/pubmed/25523634 http://dx.doi.org/10.1186/1745-6215-15-492

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