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Enhanced Wnt/β-catenin and Notch signalling in the activated canine hepatic progenitor cell niche

BACKGROUND: The liver has a large regenerative capacity. Hepatocytes can replicate and regenerate a diseased liver. However, as is the case in severe liver diseases, this replication may become insufficient or exhausted and hepatic progenitor cells (HPCs) can be activated in an attempt to restore li...

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Detalles Bibliográficos
Autores principales: Schotanus, Baukje A, Kruitwagen, Hedwig S, van den Ingh, Ted SGAM, van Wolferen, Monique E, Rothuizen, Jan, Penning, Louis C, Spee, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302101/
https://www.ncbi.nlm.nih.gov/pubmed/25551829
http://dx.doi.org/10.1186/s12917-014-0309-1