Specifying the target difference in the primary outcome for a randomised controlled trial: guidance for researchers

BACKGROUND: Central to the design of a randomised controlled trial is the calculation of the number of participants needed. This is typically achieved by specifying a target difference and calculating the corresponding sample size, which provides reassurance that the trial will have the required sta...

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Detalles Bibliográficos
Autores principales: Cook, Jonathan A, Hislop, Jenni, Altman, Douglas G, Fayers, Peter, Briggs, Andrew H, Ramsay, Craig R, Norrie, John D, Harvey, Ian M, Buckley, Brian, Fergusson, Dean, Ford, Ian, Vale, Luke D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302137/
https://www.ncbi.nlm.nih.gov/pubmed/25928502
http://dx.doi.org/10.1186/s13063-014-0526-8

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