Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis

Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa. The aim of this study was to test Haliscosamine...

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Detalles Bibliográficos
Autores principales: El Amraoui, Belakssem, Biard, Jean François, Ikbal, Fatima Ez-Zohra, El Wahidi, Majida, Kandil, Mostafa, El Amraoui, Mohammed, Fassouane, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302159/
https://www.ncbi.nlm.nih.gov/pubmed/25625038
http://dx.doi.org/10.1186/s40064-015-0797-x
Descripción
Sumario:Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa. The aim of this study was to test Haliscosamine in vitro and in vivo for its antifungal activity against Fusarium oxysporum f.sp. melonis causing fusarium wilt of melon. Overall, in vitro test showed that haliscosamine has a similar effect as DESOGERME SP VEGETAUX®. In addition, in vivo showed a significant effect against Fusarium oxysporum f.sp. melonis. Taking to gather, our results suggest that haliscosamine constitutes a potential candidate against Fusarium oxysporum f.sp. melonis and the possibility to use in phytopathology.

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