Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis

Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa. The aim of this study was to test Haliscosamine...

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Autores principales: El Amraoui, Belakssem, Biard, Jean François, Ikbal, Fatima Ez-Zohra, El Wahidi, Majida, Kandil, Mostafa, El Amraoui, Mohammed, Fassouane, Aziz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302159/
https://www.ncbi.nlm.nih.gov/pubmed/25625038
http://dx.doi.org/10.1186/s40064-015-0797-x
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author El Amraoui, Belakssem
Biard, Jean François
Ikbal, Fatima Ez-Zohra
El Wahidi, Majida
Kandil, Mostafa
El Amraoui, Mohammed
Fassouane, Aziz
author_facet El Amraoui, Belakssem
Biard, Jean François
Ikbal, Fatima Ez-Zohra
El Wahidi, Majida
Kandil, Mostafa
El Amraoui, Mohammed
Fassouane, Aziz
author_sort El Amraoui, Belakssem
collection PubMed
description Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa. The aim of this study was to test Haliscosamine in vitro and in vivo for its antifungal activity against Fusarium oxysporum f.sp. melonis causing fusarium wilt of melon. Overall, in vitro test showed that haliscosamine has a similar effect as DESOGERME SP VEGETAUX®. In addition, in vivo showed a significant effect against Fusarium oxysporum f.sp. melonis. Taking to gather, our results suggest that haliscosamine constitutes a potential candidate against Fusarium oxysporum f.sp. melonis and the possibility to use in phytopathology.
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spelling pubmed-43021592015-01-26 Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis El Amraoui, Belakssem Biard, Jean François Ikbal, Fatima Ez-Zohra El Wahidi, Majida Kandil, Mostafa El Amraoui, Mohammed Fassouane, Aziz Springerplus Research Marine sponges are a potential source of new molecules with diverse biological activities. We have previously isolated a sphingosine derivative, (9Z)-2-amino-docos-9-ene-1,3,13,14-tetraol (Haliscosamine) from the Moroccan sea sponge Haliclona viscosa. The aim of this study was to test Haliscosamine in vitro and in vivo for its antifungal activity against Fusarium oxysporum f.sp. melonis causing fusarium wilt of melon. Overall, in vitro test showed that haliscosamine has a similar effect as DESOGERME SP VEGETAUX®. In addition, in vivo showed a significant effect against Fusarium oxysporum f.sp. melonis. Taking to gather, our results suggest that haliscosamine constitutes a potential candidate against Fusarium oxysporum f.sp. melonis and the possibility to use in phytopathology. Springer International Publishing 2015-01-13 /pmc/articles/PMC4302159/ /pubmed/25625038 http://dx.doi.org/10.1186/s40064-015-0797-x Text en © El Amraoui et al.; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research
El Amraoui, Belakssem
Biard, Jean François
Ikbal, Fatima Ez-Zohra
El Wahidi, Majida
Kandil, Mostafa
El Amraoui, Mohammed
Fassouane, Aziz
Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
title Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
title_full Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
title_fullStr Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
title_full_unstemmed Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
title_short Activity of Haliscosamine against Fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
title_sort activity of haliscosamine against fusarium oxysporum f.sp. melonis: in vitro and in vivo analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302159/
https://www.ncbi.nlm.nih.gov/pubmed/25625038
http://dx.doi.org/10.1186/s40064-015-0797-x
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