The Ser/Thr kinase MAP4K4 drives c-Met-induced motility and invasiveness in a cell-based model of SHH medulloblastoma

Medulloblastoma (MB) comprises four molecularly and genetically distinct subgroups of embryonal brain tumors that develop in the cerebellum. MB mostly affects infants and children and is difficult to treat because of frequent dissemination of tumor cells within the leptomeningeal space. A potential...

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Detalles Bibliográficos
Autores principales: Santhana Kumar, Karthiga, Tripolitsioti, Dimitra, Ma, Min, Grählert, Jasmin, Egli, Katja B, Fiaschetti, Giulio, Shalaby, Tarek, Grotzer, Michael A, Baumgartner, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302160/
https://www.ncbi.nlm.nih.gov/pubmed/25625039
http://dx.doi.org/10.1186/s40064-015-0784-2

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