Assessing Cholesterol Storage in Live Cells and C. elegans by Stimulated Raman Scattering Imaging of Phenyl-Diyne Cholesterol

We report a cholesterol imaging method using rationally synthesized phenyl-diyne cholesterol (PhDY-Chol) and stimulated Raman scattering (SRS) microscope. The phenyl-diyne group is biologically inert and provides a Raman scattering cross section that is 88 times larger than the endogenous C = O stre...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Hyeon Jeong, Zhang, Wandi, Zhang, Delong, Yang, Yang, Liu, Bin, Barker, Eric L., Buhman, Kimberly K., Slipchenko, Lyudmila V., Dai, Mingji, Cheng, Ji-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302291/
https://www.ncbi.nlm.nih.gov/pubmed/25608867
http://dx.doi.org/10.1038/srep07930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302291/
https://www.ncbi.nlm.nih.gov/pubmed/25608867
http://dx.doi.org/10.1038/srep07930

Ejemplares similares