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Genome-wide screen for modifiers of Na(+)/K(+)ATPase alleles identifies critical genetic loci

BACKGROUND: Mutations affecting the Na(+)/ K(+)ATPase (a.k.a. the sodium-potassium pump) genes cause conditional locomotor phenotypes in flies and three distinct complex neurological diseases in humans. More than 50 mutations have been identified affecting the human ATP1A2 and ATP1A3 genes that are...

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Detalles Bibliográficos
Autores principales:	Talsma, Aaron D, Chaves, John F, LaMonaca, Alexandra, Wieczorek, Emily D, Palladino, Michael J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302446/ https://www.ncbi.nlm.nih.gov/pubmed/25476251 http://dx.doi.org/10.1186/s13041-014-0089-3

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