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Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★
In the present study, rabbits were treated with hyperbaric oxygen for 1 hour after detonator-blast- induced craniocerebral injury. Immunohistochemistry showed significantly reduced aquaporin 4 expression and adrenocorticotropic hormone expression in the pituitary gland of rabbits with craniocerebral...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302454/ https://www.ncbi.nlm.nih.gov/pubmed/25624795 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.22.008 |
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author | Huo, Jian Liu, Jiachuan Wang, Jinbiao Zhang, Yongming Wang, Chunlin Yang, Yanyan Sun, Wenjiang Xu, Shaonian |
author_facet | Huo, Jian Liu, Jiachuan Wang, Jinbiao Zhang, Yongming Wang, Chunlin Yang, Yanyan Sun, Wenjiang Xu, Shaonian |
author_sort | Huo, Jian |
collection | PubMed |
description | In the present study, rabbits were treated with hyperbaric oxygen for 1 hour after detonator-blast- induced craniocerebral injury. Immunohistochemistry showed significantly reduced aquaporin 4 expression and adrenocorticotropic hormone expression in the pituitary gland of rabbits with craniocerebral injury. Aquaporin 4 expression was positively correlated with adrenocorticotropic hormone expression. These findings indicate that early hyperbaric oxygen therapy may suppress adrenocorticotropic hormone secretion by inhibiting aquaporin 4 expression. |
format | Online Article Text |
id | pubmed-4302454 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43024542015-01-26 Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ Huo, Jian Liu, Jiachuan Wang, Jinbiao Zhang, Yongming Wang, Chunlin Yang, Yanyan Sun, Wenjiang Xu, Shaonian Neural Regen Res Research and Report: Brain Injury and Neural Regeneration In the present study, rabbits were treated with hyperbaric oxygen for 1 hour after detonator-blast- induced craniocerebral injury. Immunohistochemistry showed significantly reduced aquaporin 4 expression and adrenocorticotropic hormone expression in the pituitary gland of rabbits with craniocerebral injury. Aquaporin 4 expression was positively correlated with adrenocorticotropic hormone expression. These findings indicate that early hyperbaric oxygen therapy may suppress adrenocorticotropic hormone secretion by inhibiting aquaporin 4 expression. Medknow Publications & Media Pvt Ltd 2012-08-05 /pmc/articles/PMC4302454/ /pubmed/25624795 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.22.008 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research and Report: Brain Injury and Neural Regeneration Huo, Jian Liu, Jiachuan Wang, Jinbiao Zhang, Yongming Wang, Chunlin Yang, Yanyan Sun, Wenjiang Xu, Shaonian Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
title | Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
title_full | Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
title_fullStr | Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
title_full_unstemmed | Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
title_short | Early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
title_sort | early hyperbaric oxygen therapy inhibits aquaporin 4 and adrenocorticotropic hormone expression in the pituitary gland of rabbits with blast-induced craniocerebral injury★ |
topic | Research and Report: Brain Injury and Neural Regeneration |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302454/ https://www.ncbi.nlm.nih.gov/pubmed/25624795 http://dx.doi.org/10.3969/j.issn.1673-5374.2012.22.008 |
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