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Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts

INTRODUCTION: Bone remodelling and increased subchondral densification are important in osteoarthritis (OA). Modifications of bone vascularization parameters, which lead to ischemic episodes associated with hypoxic conditions, have been suspected in OA. Among several factors potentially involved, le...

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Detalles Bibliográficos
Autores principales:	Bouvard, Béatrice, Abed, Elie, Yéléhé-Okouma, Mélissa, Bianchi, Arnaud, Mainard, Didier, Netter, Patrick, Jouzeau, Jean-Yves, Lajeunesse, Daniel, Reboul, Pascal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302570/ https://www.ncbi.nlm.nih.gov/pubmed/25312721 http://dx.doi.org/10.1186/s13075-014-0459-3

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