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Spermine reverses lipopolysaccharide-induced memory deficit in mice

BACKGROUND: Lipopolysaccharide (LPS) induces neuroinflammation and memory deficit. Since polyamines improve memory in various cognitive tasks, we hypothesized that spermine administration reverses LPS-induced memory deficits in an object recognition task in mice. The involvement of the polyamine bin...

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Detalles Bibliográficos
Autores principales:	Frühauf, Pâmella Karina Santana, Porto Ineu, Rafael, Tomazi, Lediane, Duarte, Thiago, Mello, Carlos Fernando, Rubin, Maribel Antonello
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302583/ https://www.ncbi.nlm.nih.gov/pubmed/25573647 http://dx.doi.org/10.1186/s12974-014-0220-5

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