Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides

KEY CLINICAL MESSAGE: It's important to assess cases both clinically and pathologically for factors potentially predictive of an aggressive clinical course. We concluded that the relative immunosuppressive effects of PD1 may contribute to tumor progression while the lack of staining for cutaneo...

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Autores principales: Ogunrinade, Olakunle, Ahn, Christine S, Gergis, Usama, Yassin, Aminah H, Magro, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302628/
https://www.ncbi.nlm.nih.gov/pubmed/25614814
http://dx.doi.org/10.1002/ccr3.103
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author Ogunrinade, Olakunle
Ahn, Christine S
Gergis, Usama
Yassin, Aminah H
Magro, Cynthia
author_facet Ogunrinade, Olakunle
Ahn, Christine S
Gergis, Usama
Yassin, Aminah H
Magro, Cynthia
author_sort Ogunrinade, Olakunle
collection PubMed
description KEY CLINICAL MESSAGE: It's important to assess cases both clinically and pathologically for factors potentially predictive of an aggressive clinical course. We concluded that the relative immunosuppressive effects of PD1 may contribute to tumor progression while the lack of staining for cutaneous lymphocyte antigen may be an additional factor facilitating distant extracutaneous migration.
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spelling pubmed-43026282015-01-22 Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides Ogunrinade, Olakunle Ahn, Christine S Gergis, Usama Yassin, Aminah H Magro, Cynthia Clin Case Rep Case Reports KEY CLINICAL MESSAGE: It's important to assess cases both clinically and pathologically for factors potentially predictive of an aggressive clinical course. We concluded that the relative immunosuppressive effects of PD1 may contribute to tumor progression while the lack of staining for cutaneous lymphocyte antigen may be an additional factor facilitating distant extracutaneous migration. Blackwell Publishing Ltd 2014-10 2014-09-15 /pmc/articles/PMC4302628/ /pubmed/25614814 http://dx.doi.org/10.1002/ccr3.103 Text en © 2014 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. http://creativecommons.org/licenses/by-nc/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Case Reports
Ogunrinade, Olakunle
Ahn, Christine S
Gergis, Usama
Yassin, Aminah H
Magro, Cynthia
Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
title Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
title_full Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
title_fullStr Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
title_full_unstemmed Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
title_short Cutaneous lymphocyte antigen expression loss and PD1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
title_sort cutaneous lymphocyte antigen expression loss and pd1 positivity in early cutaneous lesions of rapidly progressive mycosis fungoides
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302628/
https://www.ncbi.nlm.nih.gov/pubmed/25614814
http://dx.doi.org/10.1002/ccr3.103
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