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HPV-positive oropharyngeal squamous cell carcinoma is associated with TIMP3 and CADM1 promoter hypermethylation

Oropharyngeal squamous cell carcinoma (OPSCC) is associated with human papillomavirus (HPV) in a proportion of tumors. HPV-positive OPSCC is considered a distinct molecular entity with a prognostic advantage compared to HPV-negative cases. Silencing of cancer-related genes by DNA promoter hypermethy...

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Detalles Bibliográficos
Autores principales: van Kempen, Pauline M W, van Bockel, Liselotte, Braunius, Weibel W, Moelans, Cathy B, van Olst, Marina, de Jong, Rick, Stegeman, Inge, van Diest, Paul J, Grolman, Wilko, Willems, Stefan M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302669/
https://www.ncbi.nlm.nih.gov/pubmed/25065733
http://dx.doi.org/10.1002/cam4.313