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Acetylation-dependent regulation of essential iPS-inducing factors: a regulatory crossroad for pluripotency and tumorigenesis

Induced pluripotent stem (iPS) cells can be generated from somatic cells by coexpression of four transcription factors: Sox2, Oct4, Klf4, and c-Myc. However, the low efficiency in generating iPS cells and the tendency of tumorigenesis hinder the therapeutic applications for iPS cells in treatment of...

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Detalles Bibliográficos
Autores principales:	Dai, Xiangpeng, Liu, Pengda, Lau, Alan W, Liu, Yueyong, Inuzuka, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 2014
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302671/ https://www.ncbi.nlm.nih.gov/pubmed/25116380 http://dx.doi.org/10.1002/cam4.298

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