Whole exome sequencing identifies somatic ATRX mutations in pheochromocytomas and paragangliomas

Pheochromocytomas and paragangliomas (PCC/PGL) are the solid tumor type most commonly associated with an inherited susceptibility syndrome. However, very little is known about the somatic genetic changes leading to tumorigenesis or malignant transformation. Here we perform whole exome sequencing on...

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Detalles Bibliográficos
Autores principales: Fishbein, Lauren, Khare, Sanika, Wubbenhorst, Bradley, DeSloover, Daniel, D’Andrea, Kurt, Merrill, Shana, Cho, Nam Woo, Greenberg, Roger A., Else, Tobias, Montone, Kathleen, LiVolsi, Virginia, Fraker, Douglas, Daber, Robert, Cohen, Debbie L., Nathanson, Katherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302757/
https://www.ncbi.nlm.nih.gov/pubmed/25608029
http://dx.doi.org/10.1038/ncomms7140

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