VEGF(189) binds NRP1 and is sufficient for VEGF/NRP1-dependent neuronal patterning in the developing brain

The vascular endothelial growth factor (VEGFA, VEGF) regulates neurovascular patterning. Alternative splicing of the Vegfa gene gives rise to three major isoforms termed VEGF(121), VEGF(165) and VEGF(189). VEGF(165) binds the transmembrane protein neuropilin 1 (NRP1) and promotes the migration, surv...

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Detalles Bibliográficos
Autores principales: Tillo, Miguel, Erskine, Lynda, Cariboni, Anna, Fantin, Alessandro, Joyce, Andy, Denti, Laura, Ruhrberg, Christiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302834/
https://www.ncbi.nlm.nih.gov/pubmed/25519242
http://dx.doi.org/10.1242/dev.115998

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302834/
https://www.ncbi.nlm.nih.gov/pubmed/25519242
http://dx.doi.org/10.1242/dev.115998

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