Ezh2-mediated repression of a transcriptional pathway upstream of Mmp9 maintains integrity of the developing vasculature

Maintenance of vascular integrity is required for embryogenesis and organ homeostasis. However, the gene expression programs that stabilize blood vessels are poorly understood. Here, we show that the histone methyltransferase Ezh2 maintains integrity of the developing vasculature by repressing a tra...

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Detalles Bibliográficos
Autores principales: Delgado-Olguín, Paul, Dang, Lan T., He, Daniel, Thomas, Sean, Chi, Lijun, Sukonnik, Tatyana, Khyzha, Nadiya, Dobenecker, Marc-Werner, Fish, Jason E., Bruneau, Benoit G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2014
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302930/
https://www.ncbi.nlm.nih.gov/pubmed/25359725
http://dx.doi.org/10.1242/dev.112607

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