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Global O-GlcNAc Levels Modulate Transcription of the Adipocyte Secretome during Chronic Insulin Resistance

Increased flux through the hexosamine biosynthetic pathway and the corresponding increase in intracellular glycosylation of proteins via O-linked β-N-acetylglucosamine (O-GlcNAc) is sufficient to induce insulin resistance (IR) in multiple systems. Previously, our group used shotgun proteomics to ide...

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Detalles Bibliográficos
Autores principales:	Wollaston-Hayden, Edith E., Harris, Ruth B. S., Liu, Bingqiang, Bridger, Robert, Xu, Ying, Wells, Lance
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4302944/ https://www.ncbi.nlm.nih.gov/pubmed/25657638 http://dx.doi.org/10.3389/fendo.2014.00223

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