Cargando…

Methylation profiling of ductal carcinoma in situand its relationship to histopathological features

INTRODUCTION: DNA methylation is a well-studied biomarker in invasive breast cancer, but its role in ductal carcinoma in situ (DCIS) is less well characterized. The aims of this study are to assess the methylation profile in DCIS for a panel of well-characterized genes that are frequently methylated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pang, Jia-Min B, Deb, Siddhartha, Takano, Elena A, Byrne, David J, Jene, Nicholas, Boulghourjian, Alice, Holliday, Anne, Millar, Ewan, Lee, C Soon, O’Toole, Sandra A, Dobrovic, Alexander, Fox, Stephen B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303108/ https://www.ncbi.nlm.nih.gov/pubmed/25331261 http://dx.doi.org/10.1186/s13058-014-0423-9

Ejemplares similares

PIK3CA mutations are frequently observed in BRCAX but not BRCA2 -associated male breast cancer
por: Deb, Siddhartha, et al.
Publicado: (2013)

DNA methylation in ductal carcinoma in situ of the breast
por: Pang, Jia-Min B, et al.
Publicado: (2013)

BRCA2 carriers with male breast cancer show elevated tumour methylation
por: Deb, Siddhartha, et al.
Publicado: (2017)

LRH-1 expression patterns in breast cancer tissues are associated with tumour aggressiveness
por: Pang, Jia-Min B., et al.
Publicado: (2017)

Recruitment of regulatory T cells is correlated with hypoxia-induced CXCR4 expression, and is associated with poor prognosis in basal-like breast cancers
por: Yan, Max, et al.
Publicado: (2011)

Genotypic and phenotypic analysis of familial male breast cancer shows under representation of the HER2 and basal subtypes in BRCA-associated carcinomas
por: Deb, Siddhartha, et al.
Publicado: (2012)

Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast
por: Pang, Jia-Min B., et al.
Publicado: (2015)

Assessment of DNA methylation profiling and copy number variation as indications of clonal relationship in ipsilateral and contralateral breast cancers to distinguish recurrent breast cancer from a second primary tumour
por: Huang, Katie T., et al.
Publicado: (2015)

A multiplex endpoint RT-PCR assay for quality assessment of RNA extracted from formalin-fixed paraffin-embedded tissues
por: Takano, Elena A, et al.
Publicado: (2010)

Prediction of outcome of early ER+ breast cancer is improved using a biomarker panel, which includes Ki-67 and p53
por: Millar, E K A, et al.
Publicado: (2011)

No evidence for promoter region methylation of the succinate dehydrogenase and fumarate hydratase tumour suppressor genes in breast cancer
por: Huang, Katie T, et al.
Publicado: (2009)

The expression of the ubiquitin ligase SIAH2 (seven in absentia homolog 2) is mediated through gene copy number in breast cancer and is associated with a basal-like phenotype and p53 expression
por: Chan, Peter, et al.
Publicado: (2011)

Gynaecomastia-like change of a female breast with tri-layer ductal epithelium as described in the male breast
por: Fink, Teagan, et al.
Publicado: (2022)

Rapid detection of carriers with BRCA1 and BRCA2 mutations using high resolution melting analysis
por: Takano, Elena A, et al.
Publicado: (2008)

Mutational profiling of familial male breast cancers reveals similarities with luminal A female breast cancer with rare TP53 mutations
por: Deb, S, et al.
Publicado: (2014)

Histopathological and clonal study of combined lobular and ductal carcinoma of the breast
por: Tazaki, Eri, et al.
Publicado: (2013)

Development and Histopathological Characterization of Tumorgraft Models of Pancreatic Ductal Adenocarcinoma
por: Garcia, Patrick L., et al.
Publicado: (2013)

Breast Tissue Composition and Immunophenotype and Its Relationship with Mammographic Density in Women at High Risk of Breast Cancer
por: Pang, Jia-Min B., et al.
Publicado: (2015)

BAG-1 predicts patient outcome and tamoxifen responsiveness in ER-positive invasive ductal carcinoma of the breast
por: Millar, E K A, et al.
Publicado: (2009)

Prognostic and Predictive Biomarkers in Familial Breast Cancer
por: Deb, Siddhartha, et al.
Publicado: (2023)

Comparative microRNA profiling of sporadic and BRCA1 associated basal-like breast cancers
por: Yan, Max, et al.
Publicado: (2015)

Breast cancer histopathology image-based gene expression prediction using spatial transcriptomics data and deep learning
por: Rahaman, Md Mamunur, et al.
Publicado: (2023)

MCP‐1 expression in breast cancer and its association with distant relapse
por: Mulholland, Bridie S., et al.
Publicado: (2023)

Ductal carcinoma in situ of the breast: correlation between histopathological features and age of patients
por: Perez, Amanda Arantes, et al.
Publicado: (2014)

Deep learning-based grading of ductal carcinoma in situ in breast histopathology images
por: Wetstein, Suzanne C., et al.
Publicado: (2021)

Methylation-sensitive high resolution melting (MS-HRM): a new approach for sensitive and high-throughput assessment of methylation
por: Wojdacz, Tomasz K., et al.
Publicado: (2007)

SP142 PD-L1 Scoring Shows High Interobserver and Intraobserver Agreement in Triple-negative Breast Carcinoma But Overall Low Percentage Agreement With Other PD-L1 Clones SP263 and 22C3
por: Pang, Jia-Min B., et al.
Publicado: (2021)

Ductal Carcinoma In Situ Biology, Biomarkers, and Diagnosis
por: Gorringe, Kylie L., et al.
Publicado: (2017)

Enhancing histopathological image classification of invasive ductal carcinoma using hybrid harmonization techniques
por: Abdallah, Nassib, et al.
Publicado: (2023)

Large-Section Histopathology Can Better Indicate the Immune Microenvironment and Predict the Prognosis of Pancreatic Ductal Adenocarcinoma Than Small-Section Histopathology
por: Ding, Guiling, et al.
Publicado: (2021)

The influence of tumour burden and therapy on cellular cytotoxicity responses in patients with ocular and skin melanoma.
por: Unsgaard, B., et al.
Publicado: (1975)

Methylation of CALCA and CALCB in Pancreatic Ductal Adenocarcinoma
por: Gao, Feng, et al.
Publicado: (2021)

Methylation profiling of normal individuals reveals mosaic promoter methylation of cancer-associated genes
por: Kristensen, Lasse Sommer, et al.
Publicado: (2012)

COX-2 expression is predictive for early relapse and aromatase inhibitor resistance in patients with ductal carcinoma in situ of the breast, and is a target for treatment
por: Generali, D, et al.
Publicado: (2014)

Insights into female sperm storage from the spermathecal fluid proteome of the honeybee Apis mellifera
por: Baer, Boris, et al.
Publicado: (2009)

Evaluating the effectiveness of stain normalization techniques in automated grading of invasive ductal carcinoma histopathological images
por: Voon, Wingates, et al.
Publicado: (2023)

Smallpox: An attack scenario.
por: O'Toole, T
Publicado: (1999)

TILs Immunophenotype in Breast Cancer Predicts Local Failure and Overall Survival: Analysis in a Large Radiotherapy Trial with Long-Term Follow-Up
por: Millar, Ewan, et al.
Publicado: (2020)

Unsupervised subtyping and methylation landscape of pancreatic ductal adenocarcinoma
por: Roy, Shikha, et al.
Publicado: (2021)

hist2RNA: An Efficient Deep Learning Architecture to Predict Gene Expression from Breast Cancer Histopathology Images
por: Mondol, Raktim Kumar, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_unqcoebdbo8i1vif69lmlb5ugq