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Prognostic significance of FOXP3+ tumor-infiltrating lymphocytes in breast cancer depends on estrogen receptor and human epidermal growth factor receptor-2 expression status and concurrent cytotoxic T-cell infiltration

INTRODUCTION: The infiltration of FOXP3(+) regulatory T cells into invasive tumors has been reported to be associated with survival in a variety of cancers. The prognostic significance of FOXP3(+) tumor-infiltrating lymphocytes (TILs) in breast cancer, however, remains controversial. METHODS: FOXP3(...

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Detalles Bibliográficos
Autores principales: Liu, Shuzhen, Foulkes, William D, Leung, Samuel, Gao, Dongxia, Lau, Sherman, Kos, Zuzana, Nielsen, Torsten O
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303113/
https://www.ncbi.nlm.nih.gov/pubmed/25193543
http://dx.doi.org/10.1186/s13058-014-0432-8