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Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways

INTRODUCTION: Although aberrant tyrosine kinase signalling characterises particular breast cancer subtypes, a global analysis of tyrosine phosphorylation in mouse models of breast cancer has not been undertaken to date. This may identify conserved oncogenic pathways and potential therapeutic targets...

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Detalles Bibliográficos
Autores principales: Ali, Naveid A, Wu, Jianmin, Hochgräfe, Falko, Chan, Howard, Nair, Radhika, Ye, Sunny, Zhang, Luxi, Lyons, Ruth J, Pinese, Mark, Lee, Hong Ching, Armstrong, Nicola, Ormandy, Christopher J, Clark, Susan J, Swarbrick, Alexander, Daly, Roger J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303118/
https://www.ncbi.nlm.nih.gov/pubmed/25200860
http://dx.doi.org/10.1186/s13058-014-0437-3