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Profiling the tyrosine phosphoproteome of different mouse mammary tumour models reveals distinct, model-specific signalling networks and conserved oncogenic pathways
INTRODUCTION: Although aberrant tyrosine kinase signalling characterises particular breast cancer subtypes, a global analysis of tyrosine phosphorylation in mouse models of breast cancer has not been undertaken to date. This may identify conserved oncogenic pathways and potential therapeutic targets...
Autores principales: | Ali, Naveid A, Wu, Jianmin, Hochgräfe, Falko, Chan, Howard, Nair, Radhika, Ye, Sunny, Zhang, Luxi, Lyons, Ruth J, Pinese, Mark, Lee, Hong Ching, Armstrong, Nicola, Ormandy, Christopher J, Clark, Susan J, Swarbrick, Alexander, Daly, Roger J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303118/ https://www.ncbi.nlm.nih.gov/pubmed/25200860 http://dx.doi.org/10.1186/s13058-014-0437-3 |
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