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Functional variants at the 21q22.3 locus involved in breast cancer progression identified by screening of genome-wide estrogen response elements

INTRODUCTION: Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the regulatory region of estrogen-responsive genes and regulates their transcription. Sequence variants in the regulatory regions have the potential to affect the transcription f...

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Detalles Bibliográficos
Autores principales: Hsiung, Chia-Ni, Chu, Hou-Wei, Huang, Yuan-Ling, Chou, Wen-Cheng, Hu, Ling-Yueh, Hsu, Huan-Ming, Wu, Pei-Ei, Hou, Ming-Feng, Yu, Jyh-Cherng, Shen, Chen-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303134/
https://www.ncbi.nlm.nih.gov/pubmed/25298020
http://dx.doi.org/10.1186/s13058-014-0455-1