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Functional variants at the 21q22.3 locus involved in breast cancer progression identified by screening of genome-wide estrogen response elements
INTRODUCTION: Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the regulatory region of estrogen-responsive genes and regulates their transcription. Sequence variants in the regulatory regions have the potential to affect the transcription f...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303134/ https://www.ncbi.nlm.nih.gov/pubmed/25298020 http://dx.doi.org/10.1186/s13058-014-0455-1 |