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Investigation of cyanine dyes for in vivo optical imaging of altered mitochondrial membrane potential in tumors

Mitochondrial membrane potential (Δψ(m)) alteration is an important target for cancer diagnosis. In this study, we designed a series of near-infrared fluorescent cationic cyanine dyes with varying alkyl chain lengths (IC7-1 derivatives) to provide diverse lipophilicities and serum albumin-binding ra...

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Detalles Bibliográficos
Autores principales:	Onoe, Satoru, Temma, Takashi, Shimizu, Yoichi, Ono, Masahiro, Saji, Hideo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303146/ https://www.ncbi.nlm.nih.gov/pubmed/24737784 http://dx.doi.org/10.1002/cam4.252

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