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U-251 revisited: genetic drift and phenotypic consequences of long-term cultures of glioblastoma cells
It is well known that in vitro subculture represents a selection pressure on cell lines, and over time this may result in a genetic drift in the cancer cells. In addition, long-term cultures harbor the risk of cross-contamination with other cell lines. The consequences may have major impact on exper...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BlackWell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303149/ https://www.ncbi.nlm.nih.gov/pubmed/24810477 http://dx.doi.org/10.1002/cam4.219 |