Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells

INTRODUCTION: Luminal, estrogen receptor-positive (ER(+)) breast cancers can metastasize but lie dormant for years before recurrences prove lethal. Understanding the roles of estrogen (E) or progestin (P) in development of luminal metastases or in arousal from dormancy is hindered by few preclinical...

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Detalles Bibliográficos
Autores principales: Ogba, Ndiya, Manning, Nicole G, Bliesner, Brian S, Ambler, S Kelly, Haughian, James M, Pinto, Mauricio P, Jedlicka, Paul, Joensuu, Kristiina, Heikkilä, Päivi, Horwitz, Kathryn B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303198/
https://www.ncbi.nlm.nih.gov/pubmed/25475897
http://dx.doi.org/10.1186/s13058-014-0489-4

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