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Shift in GATA3 functions, and GATA3 mutations, control progression and clinical presentation in breast cancer

INTRODUCTION: GATA binding protein 3 (GATA3) is a regulator of mammary luminal cell differentiation, and an estrogen receptor (ER) associated marker in breast cancer. Tumor suppressor functions of GATA3 have been demonstrated primarily in basal-like breast cancers. Here, we focused on its function i...

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Detalles Bibliográficos
Autores principales: Cohen, Helit, Ben-Hamo, Rotem, Gidoni, Moriah, Yitzhaki, Ilana, Kozol, Renana, Zilberberg, Alona, Efroni, Sol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303202/
https://www.ncbi.nlm.nih.gov/pubmed/25410484
http://dx.doi.org/10.1186/s13058-014-0464-0

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