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Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer
Cancer genomic DNA sequences enable identification of all mutations and suggest targets for precision medicine. The identities and patterns of the mutations themselves also provide critical information for deducing the originating DNA damaging agents, causal molecular mechanisms, and thus additional...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303225/ https://www.ncbi.nlm.nih.gov/pubmed/25848704 http://dx.doi.org/10.1186/s13058-014-0498-3 |