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Variability in Tuberculosis Granuloma T Cell Responses Exists, but a Balance of Pro- and Anti-inflammatory Cytokines Is Associated with Sterilization

Lung granulomas are the pathologic hallmark of tuberculosis (TB). T cells are a major cellular component of TB lung granulomas and are known to play an important role in containment of Mycobacterium tuberculosis (Mtb) infection. We used cynomolgus macaques, a non-human primate model that recapitulat...

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Detalles Bibliográficos
Autores principales:	Gideon, Hannah Priyadarshini, Phuah, JiaYao, Myers, Amy J., Bryson, Bryan D., Rodgers, Mark A., Coleman, M. Teresa, Maiello, Pauline, Rutledge, Tara, Marino, Simeone, Fortune, Sarah M., Kirschner, Denise E., Lin, Philana Ling, Flynn, JoAnne L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303275/ https://www.ncbi.nlm.nih.gov/pubmed/25611466 http://dx.doi.org/10.1371/journal.ppat.1004603

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