Molecular Basis for the Catalytic Specificity of the CTX-M Extended-Spectrum β-Lactamases

[Image: see text] Extended-spectrum β-lactamases (ESBLs) pose a threat to public health because of their ability to confer resistance to extended-spectrum cephalosporins such as cefotaxime. The CTX-M β-lactamases are the most widespread ESBL enzymes among antibiotic resistant bacteria. Many of the a...

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Detalles Bibliográficos
Autores principales: Adamski, Carolyn J., Cardenas, Ana Maria, Brown, Nicholas G., Horton, Lori B., Sankaran, Banumathi, Prasad, B. V. Venkataram, Gilbert, Hiram F., Palzkill, Timothy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303298/
https://www.ncbi.nlm.nih.gov/pubmed/25489790
http://dx.doi.org/10.1021/bi501195g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303298/
https://www.ncbi.nlm.nih.gov/pubmed/25489790
http://dx.doi.org/10.1021/bi501195g

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