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The role of Ca(2+) influx in endocytic vacuole formation in pancreatic acinar cells
The inducers of acute pancreatitis trigger a prolonged increase in the cytosolic Ca(2+) concentration ([Ca(2+)](c)), which is responsible for the damage to and eventual death of pancreatic acinar cells. Vacuolization is an important indicator of pancreatic acinar cell damage. Furthermore, activation...
Autores principales: | Voronina, Svetlana, Collier, David, Chvanov, Michael, Middlehurst, Ben, Beckett, Alison J., Prior, Ian A., Criddle, David N., Begg, Malcolm, Mikoshiba, Katsuhiko, Sutton, Robert, Tepikin, Alexei V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303308/ https://www.ncbi.nlm.nih.gov/pubmed/25370603 http://dx.doi.org/10.1042/BJ20140398 |
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