Cargando…

Human in Vivo Pharmacokinetics of [(14)C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Microdosing

[Image: see text] Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human carcino...

Descripción completa

Detalles Bibliográficos
Autores principales:	Madeen, Erin, Corley, Richard A., Crowell, Susan, Turteltaub, Kenneth, Ognibene, Ted, Malfatti, Mike, McQuistan, Tammie J., Garrard, Mary, Sudakin, Dan, Williams, David E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2014
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303324/ https://www.ncbi.nlm.nih.gov/pubmed/25418912 http://dx.doi.org/10.1021/tx5003996

Ejemplares similares

Hypomethylated Fgf3 is a potential biomarker for early detection of oral cancer in mice treated with the tobacco carcinogen dibenzo[def,p]chrysene
por: Sun, Yuan-Wan, et al.
Publicado: (2017)

Electrochemical and spectroscopic properties of twisted dibenzo[g,p]chrysene derivatives
por: Imai, Tomoya, et al.
Publicado: (2022)

Luminescent Tetranuclear Gold(I) Dibenzo[g,p]chrysene Derivatives: Effect of the Environment on Photophysical Properties
por: Caparrós, Francisco J., et al.
Publicado: (2020)

Campos escalares y vectoriales : interpretación física
por: McQuistan, Richmond
Publicado: (1969)

Chrysene‐Based Blue Emitters
por: Nathusius, Marvin, et al.
Publicado: (2020)

Degradation of Chrysene by Enriched Bacterial Consortium
por: Vaidya, Sagar, et al.
Publicado: (2018)

Teaching Dental Drawings for Freshman Dental Students and Its Correlation with Manual Dexterity
por: Elgendy, Hanan, et al.
Publicado: (2023)

Pharmacokinetics and Pharmacodynamics of Lysergic Acid Diethylamide Microdoses in Healthy Participants
por: Holze, Friederike, et al.
Publicado: (2020)

Differential cellular metabolite alterations in HaCaT cells caused by exposure to the aryl hydrocarbon receptor-binding polycyclic aromatic hydrocarbons chrysene, benzo[a]pyrene and dibenzo[a,l]pyrene
por: Potratz, Sarah, et al.
Publicado: (2016)

Dose‐linearity of the pharmacokinetics of an intravenous [(14)C]midazolam microdose in children
por: van Groen, Bianca D., et al.
Publicado: (2019)

Editorial: Helping meet oral health needs in underserved communities
por: Weatherspoon, Darien J., et al.
Publicado: (2023)

The Mammalian Calcium-binding Protein, Nucleobindin (CALNUC), Is a Golgi Resident Protein
por: Lin, Ping, et al.
Publicado: (1998)

Protective effects of lipoic acid on chrysene-induced toxicity on Müller cells in vitro
por: Mansoor, Saffar, et al.
Publicado: (2013)

Carborane‐Induced Excimer Emission of Severely Twisted Bis‐o‐Carboranyl Chrysene
por: Marsh, Adam V., et al.
Publicado: (2018)

Self-Rated Effectiveness of Microdosing With Psychedelics for Mental and Physical Health Problems Among Microdosers
por: Hutten, Nadia R. P. W., et al.
Publicado: (2019)

Microdosing: Concept, Application and Relevance
por: Tewari, Tushar, et al.
Publicado: (2010)

Asking questions of psychedelic microdosing
por: Cameron, Lindsay P
Publicado: (2021)

The interactive effects of oral health literacy and acculturation on dental care use among Hispanic adults
por: Nguyen, Daisy Patiño, et al.
Publicado: (2022)

Diccionario de especialidades farmacéuticas, DEF.
Publicado: (2016)

Diccionario de especialidades farmacéuticas, DEF.
Publicado: (2014)

Diccionario de especialidades farmacéuticas, DEF.
Publicado: (2013)

Sirt1: Def-eating senescence?
por: Fusco, Salvatore, et al.
Publicado: (2012)

Influence of ligand’s directional configuration, chrysenes as model compounds, on the binding activity with aryl hydrocarbon receptor
por: Kim, Taewoo, et al.
Publicado: (2020)

A systematic study of microdosing psychedelics
por: Polito, Vince, et al.
Publicado: (2019)

The therapeutic potential of microdosing psychedelics in depression
por: Kuypers, Kim P.C.
Publicado: (2020)

Accelerator mass spectrometry for measuring low-dose carcinogen binding to DNA.
por: Felton, J S, et al.
Publicado: (1994)

Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3
por: Guan, Yihong, et al.
Publicado: (2016)

Adults who microdose psychedelics report health related motivations and lower levels of anxiety and depression compared to non-microdosers
por: Rootman, Joseph M., et al.
Publicado: (2021)

Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls
por: Rootman, Joseph M., et al.
Publicado: (2022)

Recent advances in biomedical applications of accelerator mass spectrometry
por: Hah, Sang Soo, et al.
Publicado: (2009)

Phase 0 - Microdosing strategy in clinical trials
por: Rani, P. Usha, et al.
Publicado: (2008)

Psychedelic microdosing benefits and challenges: an empirical codebook
por: Anderson, Thomas, et al.
Publicado: (2019)

A combined accelerator mass spectrometry/positron emission tomography microdose study to assess the plasma and brain tissue pharmacokinetics of (11)C- and (14)C-labelled verapamil in healthy volunteers
por: Wagner, Claudia C, et al.
Publicado: (2008)

Pediatric Microdose Study of [(14)C]Paracetamol to Study Drug Metabolism Using Accelerated Mass Spectrometry: Proof of Concept
por: Mooij, Miriam G., et al.
Publicado: (2014)

The intergenic region of the maize defensin-like protein genes Def1 and Def2 functions as an embryo-specific asymmetric bidirectional promoter
por: Liu, Xiaoqing, et al.
Publicado: (2016)

Author Correction: Psilocybin microdosers demonstrate greater observed improvements in mood and mental health at one month relative to non-microdosing controls
por: Rootman, Joseph M., et al.
Publicado: (2022)

Structure-Activity Determinants in Antifungal Plant Defensins MsDef1 and MtDef4 with Different Modes of Action against Fusarium graminearum
por: Sagaram, Uma Shankar, et al.
Publicado: (2011)

Motives and Side-Effects of Microdosing With Psychedelics Among Users
por: Hutten, Nadia R P W, et al.
Publicado: (2019)

Self-blinding citizen science to explore psychedelic microdosing
por: Szigeti, Balázs, et al.
Publicado: (2021)

Buprenorphine Microdosing Cross Tapers: A Time for Change
por: Raheemullah, Amer, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j049ifcgcgqmlafbp77osodl8t