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Tailoring the Antibody Response to Aggregated Aß Using Novel Alzheimer-Vaccines

Recent evidence suggests Alzheimer-Disease (AD) to be driven by aggregated Aß. Capitalizing on the mechanism of molecular mimicry and applying several selection layers, we screened peptide libraries for moieties inducing antibodies selectively reacting with Aß-aggregates. The technology identified a...

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Detalles Bibliográficos
Autores principales:	Mandler, Markus, Santic, Radmila, Gruber, Petra, Cinar, Yeliz, Pichler, Dagmar, Funke, Susanne Aileen, Willbold, Dieter, Schneeberger, Achim, Schmidt, Walter, Mattner, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303436/ https://www.ncbi.nlm.nih.gov/pubmed/25611858 http://dx.doi.org/10.1371/journal.pone.0115237

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