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The many faces of mitophagy

Failure to maintain mitochondrial integrity is linked to age-related conditions, such as neurodegeneration. Two genes linked to Parkinson's disease, PINK1 and Parkin, play a key role in targeting the degradation of dysfunctional mitochondria (mitophagy). However, the mechanisms regulating the P...

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Detalles Bibliográficos
Autores principales: Ivatt, Rachael M, Whitworth, Alexander J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303441/
https://www.ncbi.nlm.nih.gov/pubmed/24398127
http://dx.doi.org/10.1002/embr.201338224

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