Shiga Toxin 2-Induced Endoplasmic Reticulum Stress Is Minimized by Activated Protein C but Does Not Correlate with Lethal Kidney Injury

Enterohemorrhagic Escherichia coli produce ribotoxic Shiga toxins (Stx), which are responsible for kidney injury and development of hemolytic uremic syndrome. The endoplasmic reticulum (ER) stress response is hypothesized to induce apoptosis contributing to organ injury; however, this process has be...

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Detalles Bibliográficos
Autores principales: Parello, Caitlin S. L., Mayer, Chad L., Lee, Benjamin C., Motomochi, Amanda, Kurosawa, Shinichiro, Stearns-Kurosawa, Deborah J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303821/
https://www.ncbi.nlm.nih.gov/pubmed/25609181
http://dx.doi.org/10.3390/toxins7010170

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