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Glycolysis, tumor metabolism, cancer growth and dissemination. A new pH-based etiopathogenic perspective and therapeutic approach to an old cancer question
Cancer cells acquire an unusual glycolytic behavior relative, to a large extent, to their intracellular alkaline pH (pH(i)). This effect is part of the metabolic alterations found in most, if not all, cancer cells to deal with unfavorable conditions, mainly hypoxia and low nutrient supply, in order...
Autores principales: | Alfarouk, Khalid O., Verduzco, Daniel, Rauch, Cyril, Muddathir, Abdel Khalig, Adil, H. H Bashir, Elhassan, Gamal O., Ibrahim, Muntaser E., David Polo Orozco, Julian, Cardone, Rosa Angela, Reshkin, Stephan J., Harguindey, Salvador |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303887/ https://www.ncbi.nlm.nih.gov/pubmed/25621294 |
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