Mathematical model of the Tat-Rev regulation of HIV-1 replication in an activated cell predicts the existence of oscillatory dynamics in the synthesis of viral components

BACKGROUND: The life cycle of human immunodeficiency virus type-1 (HIV-1) makes possible the realization of regulatory strategies that can lead to complex dynamical behavior of the system. We analyze the strategy which is based on two feedback mechanisms, one mediating a positive regulation of the v...

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Detalles Bibliográficos
Autores principales: Likhoshvai, Vitaly A, Khlebodarova, Tamara M, Bazhan, Sergei I, Gainova, Irina A, Chereshnev, Valery A, Bocharov, Gennady A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303933/
https://www.ncbi.nlm.nih.gov/pubmed/25564443
http://dx.doi.org/10.1186/1471-2164-15-S12-S1

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