Inflammation and Hyperglycemia Mediate Deaf1 Splicing in the Pancreatic Lymph Nodes via Distinct Pathways During Type 1 Diabetes

Peripheral tolerance is partially controlled by the expression of peripheral tissue antigens (PTAs) in lymph node stromal cells (LNSCs). We previously identified a transcriptional regulator, deformed epidermal autoregulatory factor 1 (Deaf1), that can regulate PTA expression in LNSCs of the pancreat...

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Detalles Bibliográficos
Autores principales: Yip, Linda, Fuhlbrigge, Rebecca, Taylor, Cariel, Creusot, Remi J., Nishikawa-Matsumura, Teppei, Whiting, Chan C., Schartner, Jill M., Akter, Rahima, von Herrath, Matthias, Fathman, C. Garrison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2015
Materias:
Pathophysiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303971/
https://www.ncbi.nlm.nih.gov/pubmed/25187368
http://dx.doi.org/10.2337/db14-0803

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303971/
https://www.ncbi.nlm.nih.gov/pubmed/25187368
http://dx.doi.org/10.2337/db14-0803

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