Cargando…

A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT)

Glioblastoma multiforme is the most aggressive primary tumor of the central nervous system. Glioma stem cells (GSCs), a small population of tumor cells with stem-like properties, are supposedly responsible for glioblastoma multiforme relapse after current therapies. In approximately thirty percent o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeitany, Maya, Pineda, Jose Ramon, Liu, Qingyuan, Porreca, Rosa Maria, Hoffschir, Françoise, Desmaze, Chantal, Silvestre, David C, Mailliet, Patrick, Junier, Marie-Pierre, Londoño-Vallejo, Arturo, Ségal-Bendirdjian, Evelyne, Chneiweiss, Hervé, Boussin, François D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Cancer Cell Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303977/ https://www.ncbi.nlm.nih.gov/pubmed/25175359 http://dx.doi.org/10.1002/ijc.29171

Ejemplares similares

ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition
por: Bakhos-Douaihy, Dalal, et al.
Publicado: (2019)

Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance
por: Jeitany, Maya, et al.
Publicado: (2017)

Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death
por: Gauthier, Laurent R., et al.
Publicado: (2011)

ATR contributes to telomere maintenance in human cells
por: Pennarun, Gaëlle, et al.
Publicado: (2010)

Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT)
por: Kusuma, Frances Karla, et al.
Publicado: (2023)

Role of ATM in the telomere response to the G-quadruplex ligand 360A
por: Pennarun, Gaëlle, et al.
Publicado: (2008)

Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells
por: Le Chalony, Catherine, et al.
Publicado: (2012)

Telomere clustering drives ALT
por: Min, Jaewon, et al.
Publicado: (2019)

Platinum Complexes Can Bind to Telomeres by Coordination
por: Saker, Lina, et al.
Publicado: (2018)

Effects of BRCA2 deficiency on telomere recombination in non-ALT and ALT cells
por: Sapir, Ester, et al.
Publicado: (2011)

Non-canonical Roles of Telomerase: Unraveling the Imbroglio
por: Ségal-Bendirdjian, Evelyne, et al.
Publicado: (2019)

Preferential binding of a G-quadruplex ligand to human chromosome ends
por: Granotier, Christine, et al.
Publicado: (2005)

Single-molecule analysis of subtelomeres and telomeres in Alternative Lengthening of Telomeres (ALT) cells
por: Abid, Heba Z., et al.
Publicado: (2020)

SMARCAL1 Resolves Replication Stress at ALT Telomeres
por: Cox, Kelli E., et al.
Publicado: (2016)

The Role of ATRX in the Alternative Lengthening of Telomeres (ALT) Phenotype
por: Amorim, João P., et al.
Publicado: (2016)

Telomere Length Maintenance in Cancer: At the Crossroad between Telomerase and Alternative Lengthening of Telomeres (ALT)
por: De Vitis, Marco, et al.
Publicado: (2018)

ZBTB40 is a telomere-associated protein and protects telomeres in human ALT cells
por: Zhou, Mingqing, et al.
Publicado: (2023)

Alternative lengthening of telomeres (ALT) cells viability is dependent on C-rich telomeric RNAs
por: Rosso, Ilaria, et al.
Publicado: (2023)

Telomerase regulation by the long non-coding RNA H19 in human acute promyelocytic leukemia cells
por: El Hajj, Joëlle, et al.
Publicado: (2018)

A role for monoubiquitinated FANCD2 at telomeres in ALT cells
por: Fan, Qiang, et al.
Publicado: (2009)

Alternative lengthening of telomeres (ALT) in cancer stem cells in vivo
por: Bojovic, Bojana, et al.
Publicado: (2014)

Alternative Lengthening of Telomeres (ALT) in Tumors and Pluripotent Stem Cells
por: Zhao, Shuang, et al.
Publicado: (2019)

The Molecular Mechanisms and Therapeutic Prospects of Alternative Lengthening of Telomeres (ALT)
por: Sohn, Eric J., et al.
Publicado: (2023)

Telomere length heterogeneity in ALT cells is maintained by PML-dependent localization of the BTR complex to telomeres
por: Loe, Taylor K., et al.
Publicado: (2020)

Association of BLM and BRCA1 during Telomere Maintenance in ALT Cells
por: Acharya, Samir, et al.
Publicado: (2014)

Telomere sequence content can be used to determine ALT activity in tumours
por: Lee, Michael, et al.
Publicado: (2018)

RNaseH1 regulates TERRA-telomeric DNA hybrids and telomere maintenance in ALT tumour cells
por: Arora, Rajika, et al.
Publicado: (2014)

MEDB-68. Analysis of telomeres length and Alternative Lengthening of Telomeres (ALT) in molecular subgroups of infant medulloblastoma
por: Buttarelli, Francesca Romana, et al.
Publicado: (2022)

Telomere extension by telomerase and ALT generates variant repeats by mechanistically distinct processes
por: Lee, Michael, et al.
Publicado: (2014)

Variant repeats are interspersed throughout the telomeres and recruit nuclear receptors in ALT cells
por: Conomos, Dimitri, et al.
Publicado: (2012)

Nuclear body phase separation drives telomere clustering in ALT cancer cells
por: Zhang, Huaiying, et al.
Publicado: (2020)

A critical role of telomere chromatin compaction in ALT tumor cell growth
por: Shi, Guang, et al.
Publicado: (2020)

ALT control, delete: FANCM as an anti-cancer target in Alternative Lengthening of Telomeres
por: O’Rourke, Julienne J, et al.
Publicado: (2019)

A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation
por: Marie-Egyptienne, Delphine T., et al.
Publicado: (2005)

The THO complex counteracts TERRA R-loop-mediated telomere fragility in telomerase(+) cells and telomeric recombination in ALT(+) cells
por: Fernandes, Rita Valador, et al.
Publicado: (2023)

Investigating the Effect of Mono- and Dimeric 360A G-Quadruplex Ligands on Telomere Stability by Single Telomere Length Analysis (STELA)
por: Hwang, In Pyo, et al.
Publicado: (2019)

Pro-survival role of p62 during granulocytic differentiation of acute myeloid leukemia cells
por: Ségal-Bendirdjian, Evelyne, et al.
Publicado: (2014)

The long non coding RNA H19 as a biomarker for breast cancer diagnosis in Lebanese women
por: Elias-Rizk, Tamina, et al.
Publicado: (2020)

Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX
por: Hu, Yang, et al.
Publicado: (2016)

TCGA Pan-Cancer Genomic Analysis of Alternative Lengthening of Telomeres (ALT) Related Genes
por: Armendáriz-Castillo, Isaac, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_dnv5ehcap9hd1er5p5jdesj432