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A novel device for target controlled administration and reflection of desflurane – the Mirus™
The Anaconda™ system is used to deliver inhalational sedation in the intensive care unit in mainland Europe. The new Mirus™ system also uses a reflector like the Anaconda; however, it also identifies end-tidal concentrations from the gas flow, injects anaesthetics during early inspiration, controls...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303981/ https://www.ncbi.nlm.nih.gov/pubmed/25040673 http://dx.doi.org/10.1111/anae.12798 |
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author | Bomberg, H Glas, M Groesdonk, V H Bellgardt, M Schwarz, J Volk, T Meiser, A |
author_facet | Bomberg, H Glas, M Groesdonk, V H Bellgardt, M Schwarz, J Volk, T Meiser, A |
author_sort | Bomberg, H |
collection | PubMed |
description | The Anaconda™ system is used to deliver inhalational sedation in the intensive care unit in mainland Europe. The new Mirus™ system also uses a reflector like the Anaconda; however, it also identifies end-tidal concentrations from the gas flow, injects anaesthetics during early inspiration, controls anaesthetic concentrations automatically, and can be used with desflurane, which is not possible using the Anaconda. We tested the Mirus with desflurane in the laboratory. Compared with an external gas monitor, the bias (two standard deviations) of the end-tidal concentration was 0.11 (0.29)% volume. In addition, automatic control was reasonable and maximum concentration delivered was 10.2%, which was deemed to be sufficient for clinical use. Efficiency was > 80% and was also deemed to be acceptable, but only when delivering a low concentration of desflurane (≤ 1.8%). By modifying the reflector, we improved efficiency up to a concentration of 3.6%. The Mirus appears to be a promising new device for long-term sedation with desflurane on the intensive care unit, but efficiency must be improved before routine clinical use becomes affordable. |
format | Online Article Text |
id | pubmed-4303981 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | BlackWell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-43039812015-02-02 A novel device for target controlled administration and reflection of desflurane – the Mirus™ Bomberg, H Glas, M Groesdonk, V H Bellgardt, M Schwarz, J Volk, T Meiser, A Anaesthesia Original Articles The Anaconda™ system is used to deliver inhalational sedation in the intensive care unit in mainland Europe. The new Mirus™ system also uses a reflector like the Anaconda; however, it also identifies end-tidal concentrations from the gas flow, injects anaesthetics during early inspiration, controls anaesthetic concentrations automatically, and can be used with desflurane, which is not possible using the Anaconda. We tested the Mirus with desflurane in the laboratory. Compared with an external gas monitor, the bias (two standard deviations) of the end-tidal concentration was 0.11 (0.29)% volume. In addition, automatic control was reasonable and maximum concentration delivered was 10.2%, which was deemed to be sufficient for clinical use. Efficiency was > 80% and was also deemed to be acceptable, but only when delivering a low concentration of desflurane (≤ 1.8%). By modifying the reflector, we improved efficiency up to a concentration of 3.6%. The Mirus appears to be a promising new device for long-term sedation with desflurane on the intensive care unit, but efficiency must be improved before routine clinical use becomes affordable. BlackWell Publishing Ltd 2014-11 2014-07-09 /pmc/articles/PMC4303981/ /pubmed/25040673 http://dx.doi.org/10.1111/anae.12798 Text en © 2014 The Authors. Anaesthesia published by John Wiley & Sons Ltd on behalf of Association of Anaesthetists of Great Britain and Ireland. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Original Articles Bomberg, H Glas, M Groesdonk, V H Bellgardt, M Schwarz, J Volk, T Meiser, A A novel device for target controlled administration and reflection of desflurane – the Mirus™ |
title | A novel device for target controlled administration and reflection of desflurane – the Mirus™ |
title_full | A novel device for target controlled administration and reflection of desflurane – the Mirus™ |
title_fullStr | A novel device for target controlled administration and reflection of desflurane – the Mirus™ |
title_full_unstemmed | A novel device for target controlled administration and reflection of desflurane – the Mirus™ |
title_short | A novel device for target controlled administration and reflection of desflurane – the Mirus™ |
title_sort | novel device for target controlled administration and reflection of desflurane – the mirus™ |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4303981/ https://www.ncbi.nlm.nih.gov/pubmed/25040673 http://dx.doi.org/10.1111/anae.12798 |
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