Cargando…

The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes

BACKGROUND: Interest in the measurement of health related quality of life and psychosocial functioning from the patient’s perspective in diabetes mellitus has grown in recent years. The aim of this study is to investigate the psychometric performance of and agreement between the generic EQ-5D and SF...

Descripción completa

Detalles Bibliográficos
Autores principales: Mulhern, Brendan, Meadows, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304018/
https://www.ncbi.nlm.nih.gov/pubmed/24661350
http://dx.doi.org/10.1186/1477-7525-12-42
_version_ 1782354019171172352
author Mulhern, Brendan
Meadows, Keith
author_facet Mulhern, Brendan
Meadows, Keith
author_sort Mulhern, Brendan
collection PubMed
description BACKGROUND: Interest in the measurement of health related quality of life and psychosocial functioning from the patient’s perspective in diabetes mellitus has grown in recent years. The aim of this study is to investigate the psychometric performance of and agreement between the generic EQ-5D and SF-6D and diabetes specific DHP-18 in Type 2 diabetes. This will support the future use of the measures by providing further evidence regarding their psychometric properties and the conceptual overlap between the instruments. The results will inform whether the measures can be used with confidence alongside each other to provide a more holistic profile of people with Type 2 diabetes. METHODS: A large longitudinal dataset (n = 1,184) of people with Type 2 diabetes was used for the analysis. Convergent validity was tested by examining correlations between the measures. Known group validity was tested across a range of clinical and diabetes severity indicators using ANOVA and effect size statistics. Agreement was examined using Bland-Altman plots. Responsiveness was tested by examining floor and ceiling effects and standardised response means. RESULTS: Correlations between the measures indicates that there is overlap in the constructs assessed (with correlations between 0.1 and 0.7 reported), but there is some level of divergence between the generic and condition specific instruments. Known group validity was generally good but was not consistent across all indicators included (with effect sizes from 0 to 0.74 reported). The EQ-5D and SF-6D displayed a high level of agreement, but there was some disagreement between the generic measures and the DHP-18 dimensions across the severity range. Responsiveness was higher in those who self-reported change in health (SRMs between 0.06 and 0.25). CONCLUSIONS: The psychometric assessment of the relationship between the EQ-5D, SF-6D and DHP-18 shows that all have a level of validity for use in Type 2 diabetes. This suggests that the measures can be used alongside each other to provide a more holistic assessment of with the quality of life impacts of Type 2 diabetes.
format Online
Article
Text
id pubmed-4304018
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-43040182015-01-24 The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes Mulhern, Brendan Meadows, Keith Health Qual Life Outcomes Research BACKGROUND: Interest in the measurement of health related quality of life and psychosocial functioning from the patient’s perspective in diabetes mellitus has grown in recent years. The aim of this study is to investigate the psychometric performance of and agreement between the generic EQ-5D and SF-6D and diabetes specific DHP-18 in Type 2 diabetes. This will support the future use of the measures by providing further evidence regarding their psychometric properties and the conceptual overlap between the instruments. The results will inform whether the measures can be used with confidence alongside each other to provide a more holistic profile of people with Type 2 diabetes. METHODS: A large longitudinal dataset (n = 1,184) of people with Type 2 diabetes was used for the analysis. Convergent validity was tested by examining correlations between the measures. Known group validity was tested across a range of clinical and diabetes severity indicators using ANOVA and effect size statistics. Agreement was examined using Bland-Altman plots. Responsiveness was tested by examining floor and ceiling effects and standardised response means. RESULTS: Correlations between the measures indicates that there is overlap in the constructs assessed (with correlations between 0.1 and 0.7 reported), but there is some level of divergence between the generic and condition specific instruments. Known group validity was generally good but was not consistent across all indicators included (with effect sizes from 0 to 0.74 reported). The EQ-5D and SF-6D displayed a high level of agreement, but there was some disagreement between the generic measures and the DHP-18 dimensions across the severity range. Responsiveness was higher in those who self-reported change in health (SRMs between 0.06 and 0.25). CONCLUSIONS: The psychometric assessment of the relationship between the EQ-5D, SF-6D and DHP-18 shows that all have a level of validity for use in Type 2 diabetes. This suggests that the measures can be used alongside each other to provide a more holistic assessment of with the quality of life impacts of Type 2 diabetes. BioMed Central 2014-03-24 /pmc/articles/PMC4304018/ /pubmed/24661350 http://dx.doi.org/10.1186/1477-7525-12-42 Text en Copyright © 2014 Mulhern and Meadows; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Mulhern, Brendan
Meadows, Keith
The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes
title The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes
title_full The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes
title_fullStr The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes
title_full_unstemmed The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes
title_short The construct validity and responsiveness of the EQ-5D, SF-6D and Diabetes Health Profile-18 in type 2 diabetes
title_sort construct validity and responsiveness of the eq-5d, sf-6d and diabetes health profile-18 in type 2 diabetes
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304018/
https://www.ncbi.nlm.nih.gov/pubmed/24661350
http://dx.doi.org/10.1186/1477-7525-12-42
work_keys_str_mv AT mulhernbrendan theconstructvalidityandresponsivenessoftheeq5dsf6danddiabeteshealthprofile18intype2diabetes
AT meadowskeith theconstructvalidityandresponsivenessoftheeq5dsf6danddiabeteshealthprofile18intype2diabetes
AT mulhernbrendan constructvalidityandresponsivenessoftheeq5dsf6danddiabeteshealthprofile18intype2diabetes
AT meadowskeith constructvalidityandresponsivenessoftheeq5dsf6danddiabeteshealthprofile18intype2diabetes