Estimation of salivary β-glucuronidase activity as a marker of periodontal disease: A case control study

AIM: The aim of the present study was to estimate the salivary β-glucuronidase level in healthy and diseased periodontium and to correlate the level with clinical measurement. MATERIALS AND METHODS: 70 patients were included in this study with the age ranging from 30 to 65 years. Both males and females were included. They were divided into two groups: Control having healthy periodontium (n = 20) and experimental having diseased periodontium (n = 50). The parameters recorded were probing pocket depth, probing attachment level, gingival index, β-glucuronidase activity in the saliva, number of white blood cells, neutrophils, lymphocytes count, and platelet count. RESULTS: It was observed that there was an increase in the level of salivary β-glucuronidase in the experimental subjects than in the control patients, and a significant positive linear relationship existed between salivary β-glucuronidase level and probing pocket depth in the experimental group. CONCLUSION: Level of salivary β-glucuronidase increases during inflammation in the periodontium.