Chromatin De-Compaction By The Nucleosomal Binding Protein HMGN5 Impairs Nuclear Sturdiness

In most metazoan nuclei, heterochromatin is located at the nuclear periphery in contact with the nuclear lamina, which provides mechanical stability to the nucleus. We show that in cultured cells, chromatin de-compaction by the nucleosome binding protein HMGN5 decreases the sturdiness, elasticity, a...

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Detalles Bibliográficos
Autores principales: Furusawa, Takashi, Rochman, Mark, Taher, Leila, Dimitriadis, Emilios K., Nagashima, Kunio, Anderson, Stasia, Bustin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304400/
https://www.ncbi.nlm.nih.gov/pubmed/25609380
http://dx.doi.org/10.1038/ncomms7138

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304400/
https://www.ncbi.nlm.nih.gov/pubmed/25609380
http://dx.doi.org/10.1038/ncomms7138

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