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Hydrogen Bond Network between Amino Acid Radical Intermediates on the Proton-Coupled Electron Transfer Pathway of E. coli α2 Ribonucleotide Reductase
[Image: see text] Ribonucleotide reductases (RNRs) catalyze the conversion of ribonucleotides to deoxyribonucleotides in all organisms. In all Class Ia RNRs, initiation of nucleotide diphosphate (NDP) reduction requires a reversible oxidation over 35 Å by a tyrosyl radical (Y(122)•, Escherichia coli...
Autores principales: | Nick, Thomas U., Lee, Wankyu, Koßmann, Simone, Neese, Frank, Stubbe, JoAnne, Bennati, Marina |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304443/ https://www.ncbi.nlm.nih.gov/pubmed/25516424 http://dx.doi.org/10.1021/ja510513z |
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