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Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors

BACKGROUNDS/AIMS: With development of imaging techniques, pancreatic tumors are being diagnosed more frequently. Applying the standard surgical procedures for pancreatic head tumors, such as pancreaticoduodenectomy and pylorus-preserving pancreaticoduodenectomy may seem too extensive for benign or l...

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Autores principales: Lee, Juhan, Lim, Jin Hong, Kim, Sung Hoon, Kim, Hyun Ki, Park, Seung Woo, Chung, Jae Bock, Kim, Kyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Association of Hepato-Biliary-Pancreatic Surgery 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304526/
https://www.ncbi.nlm.nih.gov/pubmed/26155226
http://dx.doi.org/10.14701/kjhbps.2013.17.3.126
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author Lee, Juhan
Lim, Jin Hong
Kim, Sung Hoon
Kim, Hyun Ki
Park, Seung Woo
Chung, Jae Bock
Kim, Kyung Sik
author_facet Lee, Juhan
Lim, Jin Hong
Kim, Sung Hoon
Kim, Hyun Ki
Park, Seung Woo
Chung, Jae Bock
Kim, Kyung Sik
author_sort Lee, Juhan
collection PubMed
description BACKGROUNDS/AIMS: With development of imaging techniques, pancreatic tumors are being diagnosed more frequently. Applying the standard surgical procedures for pancreatic head tumors, such as pancreaticoduodenectomy and pylorus-preserving pancreaticoduodenectomy may seem too extensive for benign or low-grade malignant pancreas head tumors. Duodenum-preserving pancreatic head resection (DPPHR) has been safely performed in patients with chronic pancreatitis. Recently, DPPHR has been used as a limited surgical procedure to remove benign or low-grade malignant pancreatic head lesions. This study is aimed to evaluate the results of DPPHR in benign or low-grade malignant tumors. METHODS: Between 2004 and 2012, six patients underwent DPPHR due to benign or low-grade malignant pancreas tumor. We performed this retrospective analysis based on the medical records. RESULTS: Five of six patients were diagnosed as intraductal papillary mucinous neoplasms. Remaining one patient was diagnosed as solid pseudopapillary neoplasm. The median age of patients was 60.3 (27-75) years, and the median follow-up period was 24 months. The operation time, blood loss and length of stay were 442.5 minutes, 680 ml and 19.2 days, respectively. There was no mortality. Five patients experienced complications including 1 delayed gastric empting, 2 bile duct strictures, 1 pancreatic fistula and 1 duodenal stricture. No recurrence or metastasis was found during follow-up. CONCLUSIONS: In benign and low-grade malignant lesions of pancreatic head, DPPHR could be alternative to traditional surgery. For applying DPPHR in pancreas tumor, a thorough preoperative examination and utilization of frozen section for sufficient resection margin are required.
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spelling pubmed-43045262015-07-07 Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors Lee, Juhan Lim, Jin Hong Kim, Sung Hoon Kim, Hyun Ki Park, Seung Woo Chung, Jae Bock Kim, Kyung Sik Korean J Hepatobiliary Pancreat Surg Original Article BACKGROUNDS/AIMS: With development of imaging techniques, pancreatic tumors are being diagnosed more frequently. Applying the standard surgical procedures for pancreatic head tumors, such as pancreaticoduodenectomy and pylorus-preserving pancreaticoduodenectomy may seem too extensive for benign or low-grade malignant pancreas head tumors. Duodenum-preserving pancreatic head resection (DPPHR) has been safely performed in patients with chronic pancreatitis. Recently, DPPHR has been used as a limited surgical procedure to remove benign or low-grade malignant pancreatic head lesions. This study is aimed to evaluate the results of DPPHR in benign or low-grade malignant tumors. METHODS: Between 2004 and 2012, six patients underwent DPPHR due to benign or low-grade malignant pancreas tumor. We performed this retrospective analysis based on the medical records. RESULTS: Five of six patients were diagnosed as intraductal papillary mucinous neoplasms. Remaining one patient was diagnosed as solid pseudopapillary neoplasm. The median age of patients was 60.3 (27-75) years, and the median follow-up period was 24 months. The operation time, blood loss and length of stay were 442.5 minutes, 680 ml and 19.2 days, respectively. There was no mortality. Five patients experienced complications including 1 delayed gastric empting, 2 bile duct strictures, 1 pancreatic fistula and 1 duodenal stricture. No recurrence or metastasis was found during follow-up. CONCLUSIONS: In benign and low-grade malignant lesions of pancreatic head, DPPHR could be alternative to traditional surgery. For applying DPPHR in pancreas tumor, a thorough preoperative examination and utilization of frozen section for sufficient resection margin are required. Korean Association of Hepato-Biliary-Pancreatic Surgery 2013-08 2013-08-31 /pmc/articles/PMC4304526/ /pubmed/26155226 http://dx.doi.org/10.14701/kjhbps.2013.17.3.126 Text en Copyright © 2013 by The Korean Association of Hepato-Biliary-Pancreatic Surgery http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Lee, Juhan
Lim, Jin Hong
Kim, Sung Hoon
Kim, Hyun Ki
Park, Seung Woo
Chung, Jae Bock
Kim, Kyung Sik
Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
title Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
title_full Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
title_fullStr Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
title_full_unstemmed Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
title_short Duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
title_sort duodenum-preserving pancreatic head resection in benign and low-grade malignant pancreatic tumors
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304526/
https://www.ncbi.nlm.nih.gov/pubmed/26155226
http://dx.doi.org/10.14701/kjhbps.2013.17.3.126
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