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Collaborative Computational Project for Electron cryo-Microscopy

The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communit...

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Detalles Bibliográficos
Autores principales: Wood, Chris, Burnley, Tom, Patwardhan, Ardan, Scheres, Sjors, Topf, Maya, Roseman, Alan, Winn, Martyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
EM
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304692/
https://www.ncbi.nlm.nih.gov/pubmed/25615866
http://dx.doi.org/10.1107/S1399004714018070
Descripción
Sumario:The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communities, to support practising scientists in their use of cryoEM software and finally to support software developers in producing and disseminating robust and user-friendly programs. The project is closely modelled on CCP4 for macromolecular crystallo­graphy, and areas of common interest such as model fitting, underlying software libraries and tools for building program packages are being exploited. Nevertheless, cryoEM includes a number of techniques covering a large range of resolutions and a distinct project is required. In this article, progress so far is reported and future plans are discussed.