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Collaborative Computational Project for Electron cryo-Microscopy

The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communit...

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Autores principales: Wood, Chris, Burnley, Tom, Patwardhan, Ardan, Scheres, Sjors, Topf, Maya, Roseman, Alan, Winn, Martyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
EM
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304692/
https://www.ncbi.nlm.nih.gov/pubmed/25615866
http://dx.doi.org/10.1107/S1399004714018070
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author Wood, Chris
Burnley, Tom
Patwardhan, Ardan
Scheres, Sjors
Topf, Maya
Roseman, Alan
Winn, Martyn
author_facet Wood, Chris
Burnley, Tom
Patwardhan, Ardan
Scheres, Sjors
Topf, Maya
Roseman, Alan
Winn, Martyn
author_sort Wood, Chris
collection PubMed
description The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communities, to support practising scientists in their use of cryoEM software and finally to support software developers in producing and disseminating robust and user-friendly programs. The project is closely modelled on CCP4 for macromolecular crystallo­graphy, and areas of common interest such as model fitting, underlying software libraries and tools for building program packages are being exploited. Nevertheless, cryoEM includes a number of techniques covering a large range of resolutions and a distinct project is required. In this article, progress so far is reported and future plans are discussed.
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spelling pubmed-43046922015-01-30 Collaborative Computational Project for Electron cryo-Microscopy Wood, Chris Burnley, Tom Patwardhan, Ardan Scheres, Sjors Topf, Maya Roseman, Alan Winn, Martyn Acta Crystallogr D Biol Crystallogr EM The Collaborative Computational Project for Electron cryo-Microscopy (CCP-EM) has recently been established. The aims of the project are threefold: to build a coherent cryoEM community which will provide support for individual scientists and will act as a focal point for liaising with other communities, to support practising scientists in their use of cryoEM software and finally to support software developers in producing and disseminating robust and user-friendly programs. The project is closely modelled on CCP4 for macromolecular crystallo­graphy, and areas of common interest such as model fitting, underlying software libraries and tools for building program packages are being exploited. Nevertheless, cryoEM includes a number of techniques covering a large range of resolutions and a distinct project is required. In this article, progress so far is reported and future plans are discussed. International Union of Crystallography 2015-01-01 /pmc/articles/PMC4304692/ /pubmed/25615866 http://dx.doi.org/10.1107/S1399004714018070 Text en © Wood et al. 2015 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle EM
Wood, Chris
Burnley, Tom
Patwardhan, Ardan
Scheres, Sjors
Topf, Maya
Roseman, Alan
Winn, Martyn
Collaborative Computational Project for Electron cryo-Microscopy
title Collaborative Computational Project for Electron cryo-Microscopy
title_full Collaborative Computational Project for Electron cryo-Microscopy
title_fullStr Collaborative Computational Project for Electron cryo-Microscopy
title_full_unstemmed Collaborative Computational Project for Electron cryo-Microscopy
title_short Collaborative Computational Project for Electron cryo-Microscopy
title_sort collaborative computational project for electron cryo-microscopy
topic EM
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4304692/
https://www.ncbi.nlm.nih.gov/pubmed/25615866
http://dx.doi.org/10.1107/S1399004714018070
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